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Tufts OpenCourseware
Renal stone disease (nephrolithiasis). (Image source: NIH Consensus Development Program, National Institutes of Health.)
Highlights of this Course

The importance of the kidneys is most clearly demonstrated in the presence of pathophysiologic states. The kidneys play a central role in the maintenance of the internal milieu by balancing fluid, electrolytes, and hydrogen ions to provide optimal conditions for molecular, cellular, and body system function. They also serve as the major excretory organ for metabolic byproducts, drugs, and other organic substances. Finally, the kidneys are an important endocrine organ, producing vasoactive factors, erythropoietin, and other circulating hormones.  As such, the kidneys are intricately involved in volume regulation and systemic hemodynamics. These topics are explored in the Lectures.

Course Description

This course reviews how the kidneys adapt to extra-renal disturbances and explores disorders that arise from primary defects in kidney function. In addition, the course explores the pathogenesis and therapy of chronic kidney disease and the consequences of kidney failure.

Please note that the course as presented here does not contain the full content of the course as taught at Tufts. The included content is based on material the Tufts faculty and instructors choose to include, as well as factors such as content preparation, software compatibility, and intellectual property and copyright restrictions.
Course Faculty
Scott J. Gilbert
Bertrand L. Jaber
Andrew S. Levey
Nicolaos E. Madias
Mark Sarnak
Lesley A. Stevens
James Strom
Daniel E. Weiner
Course Length
32 Hours
2nd year