31/873 Basic Human Pathology: Parts I and II, Academic Year 2007/2008

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Acute Inflammation/Wound Healing and Repair I

Authors: Michael Kahn, D.D.S., Lynn W. Solomon, D.D.S.

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	Basic Human Pathology Lecture #5 Acute Inflammation / Wound Healing & Repair I
	Overview: Tissue Responses to Damage
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Formation of Acute Inflammatory Exudate
	Formation of an Acute Inflammatory Exudate
	Clinical Effects of Acute Inflammation
	“4 + 1” Cardinal Signs of Inflammation
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Key Facts - Neutrophils
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Neutrophil Granules and Their Contents
	Acute Inflammatory Response
	Neutrophilic phagocytosis - cont’d
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	White Blood Cells (a.k.a. leukocytes or WBC’s)
	Acute Inflammatory Response
	Parulis (gum boil; abscess on the gingiva) = localized accumulation of neutrophils
	Pus draining from a fistula of an abscessed tooth
	Fibrinous Exudate – Pericardium
	Purulent Exudate of the Brain
	Abscess in the Skin = Localized Accumulation of Neutrophils
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Acute Inflammatory Response
	Cell Membrane Phospholipids
	Endogenous Mediators:
	Acute Inflammatory Response
	Biosynthesis of Leukotrienes and Lipoxins
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Overview of the Complement System
	Acute Inflammation Mechanisms
	Acute Inflammation Mechanisms
	Acute Inflammatory Response
	Acute Inflammatory Response

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