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Authors: Michael Kahn, D.D.S., Lynn W. Solomon, D.D.S.
Basic Human Pathology Lecture #5 Acute Inflammation / Wound Healing & Repair I Basic Human Pathology Lecture #5 Acute Inflammation / Wound Healing & Repair I
Overview: Tissue Responses to Damage Overview: Tissue Responses to Damage
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Formation of Acute Inflammatory Exudate Formation of Acute Inflammatory Exudate
Formation of an Acute Inflammatory Exudate Formation of an Acute Inflammatory Exudate
Clinical Effects of Acute Inflammation Clinical Effects of Acute Inflammation
“4 + 1” Cardinal Signs of Inflammation “4 + 1” Cardinal Signs of Inflammation
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Key Facts - Neutrophils Key Facts - Neutrophils
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Neutrophil Granules and Their Contents Neutrophil Granules and Their Contents
Acute Inflammatory Response Acute Inflammatory Response
Neutrophilic phagocytosis - cont’d Neutrophilic phagocytosis - cont’d
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
White Blood Cells (a.k.a. leukocytes or WBC’s) White Blood Cells (a.k.a. leukocytes or WBC’s)
Acute Inflammatory Response Acute Inflammatory Response
Parulis (gum boil; abscess on the gingiva) = localized accumulation of neutrophils Parulis (gum boil; abscess on the gingiva) = localized accumulation of neutrophils
Pus draining from a fistula of an abscessed tooth Pus draining from a fistula of an abscessed tooth
Fibrinous Exudate – Pericardium Fibrinous Exudate – Pericardium
Purulent Exudate of the Brain Purulent Exudate of the Brain
Abscess in the Skin = Localized Accumulation of Neutrophils Abscess in the Skin = Localized Accumulation of Neutrophils
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response
Cell Membrane Phospholipids Cell Membrane Phospholipids
Endogenous Mediators: Endogenous Mediators:
Acute Inflammatory Response Acute Inflammatory Response
Biosynthesis of Leukotrienes and Lipoxins Biosynthesis of Leukotrienes and Lipoxins
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Overview of the Complement System Overview of the Complement System
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammation Mechanisms Acute Inflammation Mechanisms
Acute Inflammatory Response Acute Inflammatory Response
Acute Inflammatory Response Acute Inflammatory Response