Introduction to Cardiovascular Pathophysiology
	Coronary Anatomy
	Actin-Myosin Structure
	The Sarcomere’s Contractile Proteins
	Excitation-Contraction Coupling
	Excitation-Contraction Coupling
	The Cardiac Electrical System
	The Cardiac Cycle
	Heart Sounds
	The Cardiac Cycle
	Components of Diastole
	Introduction to Cardiovascular Pathophysiology: Slide 12
	Determinants of Cardiac Output
	Determinants of Cardiac Output
	Determinants of Cardiac Output
	Determinants of Cardiac Output
	Determinants of Cardiac Output Contractility
	Left Ventricular Ejection Fraction
	Determinants of Cardiac Output
	The Pressure-Volume Loop
	The Pressure-Volume Loop Decline in Inotropy
	The Pressure-Volume Loop Increase in Afterload
	The Pressure-Volume Loop Decrease in Preload
	Pressure Volume Loop
	Flow Volume Loops (The Cardiac Cycle)
	Flow Volume Loops (The Cardiac Cycle)
	Intra Cardiac Diastolic Pressures
	Normal Intracardiac Pressures
	Hemodynamic Measurement
	Determinants of Blood Pressure
	Hypovolemic Shock (Hemorrhage, Dehydration)
	Cardiogenic Shock (Post Extensive Myocardial Infarction)
	Hypotension Secondary to Slow Heart Rate
	Hypotension Secondary to Anaphylactic Shock or Sepsis
	Measuring Vascular Resistance
	The Monophasic Action Potential (MAP)
	Monophasic Action Potential (Cardiac Muscle Cell)
	Monophasic Action Potential (Effect of Potassium Channel Blockers)
	Effect of Potassium Channel Blockage
	Monophasic Action Potential (Cardiac Muscle Cell)
	Monophasic Action Potential (Cardiac Pacemaker Cell)
	Monophasic Action Potential (Cardiac Pacemaker Cell)
	The Monophasic Action Potential
	Conduction of Cardiac Impulse
	The Cardiac Cycle

• Hazard Ranking System Report for Olin Chemical
• Introduction to Electrocardiography
• Anti Arrhythmic Agents
• Acute Inflammation/Wound Healing and Repair I
• Cellular Adaptations to Disease/Cell Injury and Death I