| Color Key | |
| Important key words or phrases. | |
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2. Captive Animal Circumstances
- Dictated by type of facility
- Animal acquisition and disposition
- USDA
- AALAC
- IACUC
3. Role of the Veterinarian
Animal Health Human health and safety
IACUC member
Animal advocate
Research resource (surgeon, etc.)
External roles - professional organizations (AALAS, AAZV, etc.)
4. Target Issues in Laboratory Animal Medicine
- Funding for animal health services
- Resistance to IACUC principles
- Space use allocation conflicts
- Medical decisions influenced by external concerns
- Animal welfare issues in public arena
5. Information Resources for Institutional Animal Care and Use Committees 1985-1999
The following material will be reviewed from Information Resources for Institutional Animal Care and Use Committees 1985-1999. AWIC Resource Series No. 7 http://www.nal.usda.gov/awic/pubs/IACUC/iacuc.htm
6. Attending Veterinarian and Adequate Veterinary Care
9 CFR, Subchapter A, Animal Welfare, 2.32. This document can be viewed at http://www.access.gpo.gov/nara/cfr/waisidx/9cfr2.html
7. Ensuring Adequate Veterinary Care: Roles and Responsibilities of Facility Owners and Attending Veterinarians
"Each research facility shall employ an attending veterinarian under formal arrangements. In the case of a part-time attending veterinarian or consultant arrangements, the formal arrangements shall include a written program of veterinary care and regularly scheduled visits to the research facility " 2004 USDA, APHIS, Animal Care.
To read the full document go to http://www.aphis.usda.gov/ac/cfr/9cfr2.html#2.33
8. Veterinary Medical Care
Excerpted from the Guide to the Care and Use of Laboratory Animals, p. 56. http://oacu.od.nih.gov/regs/guide/guidex.htm
Veterinary medical care is an essential part of an animal care and use program. Adequate veterinary care consists of effective programs for:
- Preventive medicine.
- Surveillance, diagnosis, treatment, and control of disease, including zoonosis control.
- Management of protocol-associated disease, disability, or other sequelae.
- Anesthesia and analgesia.
- Surgery and postsurgical care.
- Assessment of animal well-being.
- Euthanasia.
A veterinary-care program is the responsibility of the attending veterinarian, who is certified or has training or experience in laboratory animal science and medicine or in the care of the species being used. Some aspects of the veterinary-care program can be conducted by persons other than a veterinarian, but a mechanism for direct and frequent communication should be established to ensure that timely and accurate information is conveyed to the veterinarian on problems associated with animal health, behavior, and well-being. The veterinarian must provide guidance to investigators and all personnel involved in the care and use of animals to ensure appropriate handling, immobilization, sedation, analgesia, anesthesia, and euthanasia. The attending veterinarian must provide guidance or oversight to surgery programs and oversight of postsurgical care.
9. Adequate Veterinary Care
Public Position Statement of The American College of Laboratory Animal Medicine. This document is available at http://www.aclam.org/pub_adquate_care.html
10. Ancillary Material
10.1. Readings
10.1.1. Texts and Articles
Fox, JG, et al. Laboratory Animal Medicine, 2nd ed. Orlando, Florida: Academic Press, 2002.
Hrapkiewicz, Karen, et al. Clinical Laboratory Animal Medicine : an introduction. Iowa State University Press, 1998.
Institute of Laboratory Animal Resources (U.S.) Guide for the care and use of laboratory animals / Institute of Laboratory Animals Resources, Commission on Life Sciences, National Research Council. Washington, D.C. : National Academy Press, 1996. Full text also available online at http://oacu.od.nih.gov/regs/guide/guidex.htm
Laboratory Animal Medicine and Management edited by J.D. Reuter and M.A.Suckow. 2003-
10.1.2. Journals
Contemporary Topics in Laboratory Animal Science http://www.aalas.org/
Institute of Laboratory Animal Resources Journal http://dels.nas.edu/ilar_n/ilarhome/index.shtml
ILAR Journal is the quarterly, peer-reviewed publication of the Institute for Laboratory Animal Research (ILAR), which is a unit of the National Research Council, National Academy of Sciences. ILAR Journal provides thoughtful and timely information for all those who use, care for, and oversee the use of laboratory animals. Provides access to online version of the journal and many back issues; a searchable index is available.
Laboratory Animal Science : International Journal of Comparative and Experimental medicine http://www.aalas.org
10.2. Web Resources
Because World Wide Web Resources are most easily accessed via computer, this listing will mainly include web addresses of sites that serve as clearinghouses for specific topics. Selected web sites from universities that provide comprehensive listings of institutional policies, guidelines, and forms are also included. Other web sites may be found in each chapter; organizational websites will be found in the Organizations chapter.
Altweb http://altweb.jhsph.edu/
Altweb is a site for news, information, discussion, and resources from the field of alternatives toanimal testing. This site is a collaborative effort funded by the Alternatives Research & Development Foundation, the Doerenkamp - Zbinden Foundation, the Humane Society of the United States, the Office for Protection from Research Risks at the National Institutes of Health, and the Procter & Gamble Company. It is being developed by the Center for Alternatives to Animal Testing at Johns Hopkins University, in collaboration with the Altweb Project Team, to serve academic, industrial and government scientists, educators, the media, and the general public.
Altweb is intended to foster the development of scientifically acceptable in vitro and other alternatives to animal testing. Alternatives are defined as methods which reduce animal use, replace whole animal tests, or refine existing tests by minimizing animal distress.
Need help locating alternatives databases or funding sources? Check out Science & Regulations. Want to learn about the latest software and other computer resources available for your junior high? See Educational Resources. Want to know more about the history of the alternative movement? See General information.
American Association for Laboratory Animal Science http://www.aalas.org/
Animal Care, USDA, Animal and Plant Health Inspection Service http://www.aphis.usda.gov/ac/
This site provides access to the USDA agency that administers two laws that seek to ensure the humane handling of animals: the Animal Welfare Act (AWA) and the Horse Protection Act (HPA). Included are:
- full-text versions of the Animal Welfare Act and the Horse Protection Act, USDA animal welfare regulations, standards, and policies;
- Annual report to Congress;
- lists of licensed or registered research facilities, dealers, breeders, carriers, and exhibitors;
- fact sheets and other miscellaneous information;
- Freedom of Information records;
- publications; and
- Missing Pet Network.
Anesthesia and Analgesia of Laboratory Animalshttp://research.uiowa.edu/animal/?get=aa_regimens
Animal Welfare Information Center (AWIC), United States Department of Agriculture (USDA) http://www.nal.usda.gov/awic/
This site provides access to:
- full-text versions of all pertinent Federal laws, regulations, guidelines and policies, and links to international laws;
- AWIC newsletters;
- AWIC publications;
- links to databases, information on alternatives, farm animals, and organizations;
- links to the National Agricultural Library, Animal and Plant Health Inspection Service, Office for Protection from Research Risks, and NetVet.
Formulary for Laboratory Animals, 2nd ed. Compiles by C. Terrance Hawke and Steven L. Leary. Iowa State University Press http://dcminfo.wustl.edu/pdf/PDF/Text.pdf
Guide for the Care and Use of Laboratory Animals, Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council National Academy Press, Washington, D.C. 1996. http://oacu.od.nih.gov/regs/guide/guidex.htm Full text online version.
IACUC Training and Learning Consortium (IACUC TLC) http://www.iacuc.org/
Few people know it, but the idea for this site was first proposed by Ken Boschert several years ago. The site has been developed and maintained under the direction of Nicole Duffee, DVM, Washington University. The IACUC Training and Learning Consortium Task Force is an ad hoc committee established by the American Association for Laboratory Animal Science (AALAS) with the charges:
- To produce a comprehensive core course to train IACUC members.
- To develop, design and provide oversight for this IACUC training course.
- To develop, design and provide oversight for a Web site (www.iacuc.org) for comprehensive information and resources on all matters pertaining to IACUCs.
- To establish a listerv (IACUC-FORUM) for IACUC members and staff to encourage dynamic information exchange on the IACUC process.
- To establish an advisory group representing a national consortium of organizations with shared interest in the education and training of IACUC members to jointly sponsor the IACUC training initiative, with AALAS coordinating the effort.
This site provides access to:
- General Information | Listserv | Partners;
- Alternatives;
- Bibliography of IACUC Topics, Databases, Example Forms and Documents;
- Laws, Policies, Guidelines and Other Documents;
- Institutional Research Policies and Procedure Guidelines;
- Journals and Publications, Meetings, and Organizations;
- Training - IACUC members; and
- Training - Laboratory Animal Care and Use.
Information Resources for Institutional Animal Care and Use Committees1985-1999. AWIC Resource Series No. 7 http://www.nal.usda.gov/awic/pubs/IACUC/iacuc.htm
Institutional Animal Care and Use Committee Guidebook (NIH)http://grants.nih.gov/grants/olaw/GuideBook.pdf
Institutional Animal Care and Use Committee http://www.iacuc.org/
Intramural Animal Care and Use (ACU) Program of the National Institutes of Health (NIH)http://oacu.od.nih.gov/index.htm
Although this page is intended to serve as an information resource for NIH scientists, Animal Care and Use Committee (ACUC) members, veterinarians, animal science specialists, and other NIH staff involved in the conduct of biomedical research at NIH, the information presented is certainly of use to other animal care and use committees. A very well-done site.
Lab Animal IACUC Resource Page http://www.labanimal.com
This site is provided by Lab Animal magazine and contains the following:
- IACUC Reading RoomRecent Lab Animal articles for the IACUC member. Browse article selections, and enjoy full-text access in either PDF or HTML formats.
- Protocol Review Jerry Silverman's popular "Protocol Review" column. Join your colleagues in resolving "Great Eastern University's" IACUC quandaries. Perfect for training, or simply honing your review skills.
- Regulatory Updates
- IACUC-Related Links:
- IACUC Resources on the Web
- Alternatives
- Databases & Search Functions
- Endpoints & Pain Management Literature
- Search for Alternatives (USDA Policy 12)
- Pain & Distress
- Regulations and Policies
- Training
Massachusetts Society for Medical Research (MSMR) http://www.msmr.org/index.html
This site provides access to the MSMR Nation-Wide Resources List - an interactive listing of state biomedical research organizations and national organizations that promote biomedical research. To access the home page of MSMR, click on the Home Page icon at the bottom of the page.
National Agricultural Library's (NAL) Web Gateway to AGRICOLA (AGRICultural OnLine Access) http://agricola.nal.usda.gov/
AGRICOLA (AGRICultural OnLine Access) is a machine-readable database of bibliographic records created by the National Agricultural Library and its cooperators. Production of these records in electronic form began in 1970, but the database covers materials dating from the 16th century to the present. The records describe publications and resources encompassing all aspects of agriculture and allied disciplines, including plant and animal sciences, forestry, entomology, soil and water resources, agricultural economics, agricultural engineering, agricultural products, alternative farming practices, and food and nutrition. Auxiliary subjects that support NAL's Information Center activities, such as agricultural trade and marketing, rural information, and animal welfare, are also included.
National Library of Medicine's (NLM) Web Gateway http://gateway.nlm.nih.gov/gw/Cmd
The NLM Gateway accesses multiple retrieval systems which:
- Provide an easy way to search the 11 million references and abstracts in the MEDLINE database.
- Use PubMed's retrieval engine to link to about 400 journals for full text of articles (some publishers may require a subscription) and provide pre-computed sets of relevant MEDLINE articles;
- Offer NLM's Medical Subject Headings for searching; and
- Use Loansome Doc for document delivery services (there may be local charges).
NetVet Veterinary Resources and the Electronic Zoo http://netvet.wustl.edu/ Perhaps the Web's most comprehensive listing of animal-related web sites, NetVet & the Electronic Zoo were created by Ken Boschert, DVM, at Washington University's Division of Comparative Medicine, located in St. Louis, Missouri. Among this server's Web Pages are numerous views of Veterinary Medical and Animal resources available on the Internet and beyond. Topics include: What's New, a site Search engine, Career information, Education, Veterinary Specialties, Organizations, Meetings, Directory, E-Lists, Publications, Images, Government, Commerce, ElectronicZoo.
Office of Laboratory Animal Welfare (OLAW), NIH Office of Extramural Research http://grants.nih.gov/grants/olaw/olaw.htm This site provides access to the NIH agency that administers animal welfare assurances of Public Health Service fundholders. Information provided includes:
- Public Health Service Policy on Humane Care and Use of Laboratory Animals, March, 1996
- 1996 Guide for the Care and Use of Laboratory Animals, National Academy of Sciences
- Health Research Extension Act of 1985, Public Law 99-158, November 20, 1985, Section 495, "Animals in Research"
- Tutorial on the PHS Policy on Humane Care and Use of Laboratory Animals
- Sample Documents for Implementation of the PHS Policy on Humane Care and Use of Laboratory Animals
- Institutional Animal Care And Use Committee Guidebook, ARENA
- World Wide Web Resources for the IACUC - an excellent compilation of sites providing useful IACUC information.
University IACUC Sites
Arizona State University, Animal Care and Use http://researchnet.asu.edu/animal_care/
Florida State University Laboratory Animal Program http://www.fsu.edu/~FSULAR/home1.htm
Tufts University Animal Care and Use http://www.tufts.edu/central/research/AnimalCare.htm
University of California, IrvineAnimal Subjects http://www.rgs.uci.edu/as/index.htm
University of Florida Animal Care & Use http://nersp.nerdc.ufl.edu/~iacuc/index.html
University of Minnesota, Research Animal Resources http://www.ahc.umn.edu/rar/
University of Nebraska-Lincoln, Institutional Animal Care and Use Committee http://www.unl.edu/research/ReComp1/useccomm.shtml
University of Tennessee - Knoxville (UT-K), Office of Laboratory Animal Care http://research.utk.edu/ora/sections/compliances/olac/
10.3. Media
ACLAM Lab Animal Medicine and Science Series II CD-Rom . Great resource!!
ACLAM Career Pathway Powerpoint Presentations http://www.aclam.org/gen_careerpath.html


