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Gastrointestinal Pathophysiology
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Lectures
Diarrhea and Malabsorption
Author
: Laurence Scott Bailen, M.D.
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Pathophysiology of Diarrhea
Case Presentation
“Diarrhea is the too rapid evacuation of too fluid stools”
The Amazing Intestines
Diarrhea and Malabsorption: Slide 5
Diarrhea
Is it Diarrhea?
Pathophysiology of Diarrhea
Case Presentation
Osmotic Diarrhea
Diarrhea and Malabsorption: Slide 11
Lactose Intolerance
Fecal Osmotic Gap
Case Presentation
Pathophysiology of Diarrhea
Case Presentation
Malabsorption
Diarrhea and Malabsorption: Slide 18
Fat Malabsorption
Bile Salt Inactivation
Conditions Predisposing to Bacterial Overgrowth
Diarrhea and Malabsorption: Slide 22
Pathophysiology of Malabsorption in Bacterial Overgrowth
Diagnosis of Small Intestinal Bacterial Overgrowth Syndrome
Treatment of Small Intestinal Bacterial Overgrowth Syndrome
Increased Bile Salt Losses
Case Presentation
Defective Nutrient Hydrolysis
Tests for Pancreatic Insufficiency
Diarrhea and Malabsorption: Slide 30
Malabsorption: Mucosal Loss
Malabsorption: Mucosal Disease
Mucosal Disease: Crohn’s Disease
Celiac Sprue
Celiac Sprue: Pathogenesis
Celiac Sprue: Pathogenesis
Pathogenesis of Celiac Disease
Celiac Sprue: Pathology
Celiac Sprue: Clinical Presentation
Celiac Sprue: Associated Diseases
Celiac Sprue: Diagnosis
Celiac Disease: Treatment
Drugs Causing Malabsorption
D-Xylose Test: General Test for Malabsorption
Pathophysiology of Diarrhea
Case Presentation
Secretory Diarrhea
Fecal Osmotic Gap
Secretory Diarrhea
Abnormal Mediators
Abnormal Mediators
Diarrhea and Malabsorption: Slide 52
Case Presentation
Pathophysiology of Diarrhea
Altered Intestinal Motility
Irritable Bowel Syndrome
IBS: Symptoms
IBS: Epidemiology
Extent and Impact of IBS
IBS: Pathophysiology
Diarrhea and Malabsorption: Slide 61
Diarrhea and Malabsorption: Slide 62
Role of the Enteric Nervous System
Evolution of Hypotheses in IBS
Selected Mediators of Motility and Visceral Hypersensitivity
Serotonin and Enterochromaffin (EC) Cells in Altered GI Motility
Rome Criteria
IBS Diagnosis
Therapeutic Options for Patients with IBS
Case Presentation
Case Presentation
Explanations for Diarrhea
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