Water-Soluble Vitamins
	B-vitamins
	Water-Soluble Vitamins
	Chemical structures of folic acid and vitamin B12
	Water Soluble Nutrients: Slide 5
	...a study of the diets...
	Folate and Vitamin B12:
	Inhibiting MS Reaction
	Folate Deficiency:
	Water Soluble Nutrients: Slide 10
	Water Soluble Nutrients: Slide 12
	Widening Spectrum of Applications for Folate Metabolism in Modern Medicine
	Water Soluble Nutrients: Slide 14
	Bacterial Synthesis of Folate
	Modern Sulfa Drugs Contain an Inhibitor of DHFR as Well
	Water Soluble Nutrients: Slide 17
	Mechanisms of Cancer Cell Resistance to Methotrexate
	Newly Defined Clinical Sequelae of Subtle Folate Depletion
	Water Soluble Nutrients: Slide 20
	Folate Status and Neural Tube Defects
	Folic Acid Fortification
	B12 and Folate are Co-factors in Homocysteine Disposal
	Water Soluble Nutrients: Slide 24
	Water Soluble Nutrients: Slide 25
	Water Soluble Nutrients: Slide 26
	Folate as a Cancer Chemopreventive Agent
	Folate and Colonic Neoplasia
	Folate Metabolism
	Ethanol
	MTHFR Genotype, Folate Status
	Seminal Conclusion

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• LU3: Hand-PDF tutorial
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• Gout and Other Crystal Diseases
• Uveitis-Glaucoma-Hyphema Syndrome (UGH)