The Biology of Aging: Slide 1
	Aging
	Life Expectancy at Birth
	Compression of Morbidity
	Two Perspectives on Aging
	The Biology of Aging: Slide 6
	The Biology of Aging: Slide 7
	Physiologic Changes Predisposing to Disease and Injury
	Biologic Theories of Aging
	Possible Genes Involved in Senescence
	Evidence
	Transgenic Fruit Flies and Nematodes
	Premature Aging Syndromes
	Proposed Mechanisms
	The Biology of Aging: Slide 15
	P53 Gene and Cancer Suppression
	Stochastic Theories
	Somatic Mutation and DNA Repair
	The Biology of Aging: Slide 19
	The Disposal Soma
	Good Genes Gone Bad - Antagonistic Pleiotropy
	Inflammatory Trade-Off
	The Biology of Aging: Slide 23
	The Biology of Aging: Slide 24
	When to Intervene?
	Primary Prevention in Older Adults
	Nutrition
	Hormones
	Favorable Effects of Exercise on Aging
	Exercise in Older Adults
	Exercise in Older Adults (continued)
	Case
	Case (continued)
	Want to live a long time?

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