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Author: Daniel B. Carr
Cancer Pain and Symptom Control:  A Walk Through the Evidence Cancer Pain and Symptom Control: A Walk Through the Evidence
Meeting Basic Human Needs Meeting Basic Human Needs
Recognizing Undertreatment Recognizing Undertreatment
Background: Guidelines Background: Guidelines
G. B. Shaw (1856-1950) G. B. Shaw (1856-1950)
Cancer Pain: Slide 6 Cancer Pain: Slide 6
1992 AHCPR Acute Pain Guideline: 4 Major Goals 1992 AHCPR Acute Pain Guideline: 4 Major Goals
EBP (Sackett et al, BMJ 1996) EBP (Sackett et al, BMJ 1996)
An Evidence-Based Guideline An Evidence-Based Guideline
Maimonides (1135-1204 C.E.) on Bias Maimonides (1135-1204 C.E.) on Bias
Evidence: Levels Evidence: Levels
Cancer Pain: Slide 12 Cancer Pain: Slide 12
Evidence: Strength, Consistency Evidence: Strength, Consistency
Systematic Review: a Process to Minimize Bias Systematic Review: a Process to Minimize Bias
Cancer Pain: Slide 15 Cancer Pain: Slide 15
But First… But First…
Measuring Analgesic Efficacy Measuring Analgesic Efficacy
Number Needed to Treat (NNT) Number Needed to Treat (NNT)
League Table of Analgesics League Table of Analgesics
Cancer Pain: Slide 20 Cancer Pain: Slide 20
Cancer Pain: Slide 21 Cancer Pain: Slide 21
Findings of Cumulative M-A Findings of Cumulative M-A
Citations Screened for AHRQ Cancer Pain Report Citations Screened for AHRQ Cancer Pain Report
Background: EPC Reviews Background: EPC Reviews
EPC 2002: Methods (1) EPC 2002: Methods (1)
Methods (2) Methods (2)
Reporting the Evidence Reporting the Evidence
Prevalence: Pain Prevalence: Pain
Prevalence: Depression Prevalence: Depression
Prevalence: Fatigue Prevalence: Fatigue
Assessment: Pain Assessment: Pain
Assessment: Depression Assessment: Depression
Assessment: Fatigue Assessment: Fatigue
“Pain Evidence”: Problems “Pain Evidence”: Problems
Treatment: Pain (1) Treatment: Pain (1)
Treatment: Pain (2) Treatment: Pain (2)
Treatment: Pain (3) Treatment: Pain (3)
Treatment: Pain (4) Treatment: Pain (4)
Treatment: Pain (5) Treatment: Pain (5)
Treatment: Depression (1) Treatment: Depression (1)
Treatment: Depression (2) Treatment: Depression (2)
Treatment: Depression (3) Treatment: Depression (3)
Treatment: Depression (4) Treatment: Depression (4)
Treatment: Depression (5) Treatment: Depression (5)
Treatment: Depression (6) Treatment: Depression (6)
Treatment: Fatigue (1) Treatment: Fatigue (1)
Treatment: Fatigue (2) Treatment: Fatigue (2)
Treatment: Fatigue (3) Treatment: Fatigue (3)
Treatment:  Fatigue (4) Treatment: Fatigue (4)
Treatment: Fatigue (5) Treatment: Fatigue (5)
In an Ideal World... In an Ideal World...
Future Research: Pain (1) Future Research: Pain (1)
Future Research: Pain (2) Future Research: Pain (2)
Future Research: Depression Future Research: Depression
Future Research:  Fatigue Future Research: Fatigue
Marcus Aurelius Marcus Aurelius
Participants Participants