Tufts OpenCourseware
Authors: Soledad Cepeda, M.D.,Ph.D., Daniel B. Carr

1. Content and Objectives

  • Introduction to acute pain

  • Immediate and intermediate outcomes of postoperative pain control

  • Long-term outcomes: the pre-emptive analgesia controversy

  • Clinical Interventions:

    • Intravenous patient-controlled analgesia

    • Epidural analgesia and patient-controlled epidural analgesia

2. Required Readings

  • Ballantyne JC, Carr DB, et al. The comparative effects of postoperative analgesic therapies on pulmonary outcome: cumulative meta-analysis of randomized, controlled trials. Anesth Analg 1998;86:598-612.

  • Dahl JB, Moiniche S. Pre-emptive analgesia. Br Med Bull 2004; 71: 13-27.

  • Dolin SJ, Cashman JN, Bland JM. Effectiveness of acute postoperative pain management: I. Evidence from published data. Br J Anaesth 2002;89:409-23.

  • Hudcova J, McNicol E, et al. Patient controlled intravenous opioid analgesia versus conventional opioid analgesia for postoperative pain control: A quantitative systematic review. Acute Pain 2005;7:115-132.