Introduction to Glomerular Filtration
	Objectives
	Glomerular Filtrate
	Starling’s Forces
	Filtration Pressure
	Filtration Pressure
	Euvolemia
	Glomerular Membrane
	Membrane Properties
	Filtration Barrier
	Endothelium
	Endothelium
	Glomerular Epithelium (podocytes)
	Foot Process and Slit Diaphragm
	Glomerular Filtration Rate
	Factors that Affect GFR
	Filtration Fraction
	Auto-regulation
	Renal Resistance
	Auto-regulation
	Mediators of GFR Regulation
	Vascular Tone
	Tubuloglomerular Feedback
	Angiotensin II
	Angiotensin Blockade and GFR
	Sympathetic Activity and Prostaglandins
	Mediators of GFR
	Clearance
	Measuring Glomerular Filtration Rate
	Measuring Renal Plasma Flow
	Factor Influencing Clearance
	Estimating GFR
	Formulas for Monitoring Kidney Function and Estimating GFR
	Summary

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