1. HIV Transmission

2. Epidemiology of HIV

Developed world initial infection spread through homosexual males, IVDU
In resource poor settings, transmission is mainly through heterosexual sex, vertical transmission, or IVDU
In 2000, AIDS was the 7th leading cause of death in the US C. Significant increasing incidence in percentage of AIDS deaths in females
Prevalance in Caucasians decreasing, Blacks increasing, Hispanics and Asians remain stable
42 million individuals worldwide estimated to be living with HIV/AIDS as of 2002
5 million newly infected adults and children in 2002
3.1 million estimated adult and child deaths from HIV/AIDS during 2002

. Early phase when CD4 count greather than 200
1. TB
2. Candida
3. Cryptococcus
4. Histoplasmosis
5. Recurrent bacterial infection
Late phase when CD4 count is less than 200
1. Pneumocystis carinii pneumonia - give primary prophylaxis
2. Chronic cryptosporidia
Late phase when CD4 count drops below 100
1. Toxoplasmosis
2. Cytomegalovirus infection - secondary prophylaxis recommended
3. Mycobacterium avian-intracellulaire

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