Lecture 1 - Overview of Host-Parasite Interactions
1. Common infection pathway
- Encounter
- Exogenous, endogenous, or nosocomial
- Entry - ability to colonize within host
- Ingestion, inhalation, cutaneous, insect vectors, colonization factors
- Spread - local or move to another tissue site
- Multiplication
- Damage
- Outcome
2. Bacterial Groups
- A. single-cell prokaryotes
- Gram stain - based on cell wall structure
- Gram positive has thick peptidoglycan cell wall
- Cocci
- Streptococci
- Staphylococci
- Rods - straight or curved
- Mostly anaerobes
- Clostridium
- Cocci
- Gram negative has thin cell wall and outer lipid bilayer with lipopolysaccharide
- Cocci
- Meningococci
- Gonococci
- Rods
- Enterics
- Fastidious organisms
- Haemophilus
- Bordetella
- Campylobacter
- Helicobacter
- Cocci
- Spirochetes
- Acid Fast
- Mycobacteria stain with acid fast