Rheumatoid Arthritis
	Objectives
	Patient Presentation
	Patient Presentation, Cont’d
	Salient Features
	The Normal Synovium
	Chronic Inflammatory Arthritis
	Types of Chronic Inflammatory Arthritis
	Patterns
	Patterns of Arthritis
	Rheumatoid Arthritis: Epidemiology
	Rheumatoid Arthritis: Risk Factors
	Rheumatoid Arthritis: Clinical Features
	Rheumatoid Arthritis: Extrarticular Features
	Rheumatoid Arthritis: Laboratory Features
	Rheumatoid Factor
	Rheumatoid Arthritis: Pathogenesis
	T cells provide immune response to antigens
	Rheumatoid Arthritis: Treatment Considerations
	Rheumatoid Arthritis: Treatment Considerations
	Nonsteroidal Antinflammatory Agents
	DMARDS (Disease Modifying AntiRheumatic Drugs)
	DMARDs, Cont’d
	Biological Therapies
	Role of B Cells in RA
	Other B Cell Targets
	Patient Presentation
	Patient Presentation, Cont’d
	Salient Features
	Treatment

• Gout and Other Crystal Diseases
• Gout and Other Crystal Diseases
• Scalpel Tissue Biopsy
• Treatment of Lupus Nephritis – NIH Data
• Oral Pathology: Physical Examination
• Resources