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Author: David Thaler, M.D.,Ph.D.
Stroke Syndromes Stroke Syndromes
Brain Attack! Brain Attack!
Impact of acute ischemic stroke Impact of acute ischemic stroke
Estimated prevalence of stroke by age and sex Estimated prevalence of stroke by age and sex
Modifiable and non-modifiable risk factors Modifiable and non-modifiable risk factors
Symptoms of stroke Symptoms of stroke
Stroke Syndrome: Slide 7 Stroke Syndrome: Slide 7
Branches of the middle cerebral artery Branches of the middle cerebral artery
Vascular territories - Coronal section Vascular territories - Coronal section
Vascular territories - Medulla Vascular territories - Medulla
Stroke Subtypes Stroke Subtypes
Four types of intracranial hemorrhage Four types of intracranial hemorrhage
Intracerebral hemorrhage: Causes Intracerebral hemorrhage: Causes
Hypertensive ICH: Locations Hypertensive ICH: Locations
Intracerebral hemorrhage: Symptoms/Signs Intracerebral hemorrhage: Symptoms/Signs
Lobar hemorrhage Lobar hemorrhage
Putamenal hemorrhage Putamenal hemorrhage
Intracerebral hemorrhage: Treatment Intracerebral hemorrhage: Treatment
Aneurysms Aneurysms
Cerebral aneurysms: Symptoms Cerebral aneurysms: Symptoms
Stroke Syndrome: Slide 21 Stroke Syndrome: Slide 21
Subarachnoid hemorrhage: Symptoms Subarachnoid hemorrhage: Symptoms
Subarachnoid hemorrhage: Signs Subarachnoid hemorrhage: Signs
Subarachnoid hemorrhage: Diagnosis Subarachnoid hemorrhage: Diagnosis
Subarachnoid hemorrhage Subarachnoid hemorrhage
Subarachnoid hemorrhage Subarachnoid hemorrhage
Hunt and Hess Classification of subarachnoid hemorrhage Hunt and Hess Classification of subarachnoid hemorrhage
Subarachnoid hemorrhage: Major concerns Subarachnoid hemorrhage: Major concerns
Subarachnoid hemorrhage: Management Subarachnoid hemorrhage: Management
Arteriovenous malformation (AVM) Arteriovenous malformation (AVM)
Arteriovenous malformation (AVM): Symptoms Arteriovenous malformation (AVM): Symptoms
Arteriovenous malformation (AVM) Arteriovenous malformation (AVM)
Arteriovenous malformation (AVM): Treatment Arteriovenous malformation (AVM): Treatment
Stroke Subtypes Stroke Subtypes
Stroke: Definition Stroke: Definition
Stroke defined by pace Stroke defined by pace
What is the underlying mechanism? What is the underlying mechanism?
Common mechanisms of cerebral ischemia Common mechanisms of cerebral ischemia
Etiology of ischemic stroke Etiology of ischemic stroke
Small vessel disease Small vessel disease
Stroke Syndrome: Slide 42 Stroke Syndrome: Slide 42
Major lacunar syndromes (C.Miller Fisher) Major lacunar syndromes (C.Miller Fisher)
Lacunar stroke (0.2-15mm3) Lacunar stroke (0.2-15mm3)
Other causes of cerebral ischemia Other causes of cerebral ischemia
Ms I.C. Ms I.C.
Carotid dissection Carotid dissection
Mimics of cerebral ischemia Mimics of cerebral ischemia
Risk for stroke after transient ischemic attack (TIA) Risk for stroke after transient ischemic attack (TIA)
Unstable angina of the brain Unstable angina of the brain
Transcranial ultrasound Transcranial ultrasound
Baseline: Conventional T2 vs. Diffusion Baseline: Conventional T2 vs. Diffusion
24 Hours: Conventional T2 vs. Diffusion 24 Hours: Conventional T2 vs. Diffusion
Diffusion/Perfusion mismatch Diffusion/Perfusion mismatch
Diffusion/Perfusion match Diffusion/Perfusion match
Conventional angiography Conventional angiography
Carotid angiogramInternal carotid artery stenosis Carotid angiogramInternal carotid artery stenosis
Carotid artery disease Carotid artery disease
Carotid artery stenosis: Treatment Carotid artery stenosis: Treatment
Proximal aortic atherosclerosis Proximal aortic atherosclerosis
Cardiac conditions associated with cerebral embolism Cardiac conditions associated with cerebral embolism
Cardiac conditions associated with cerebral embolism Cardiac conditions associated with cerebral embolism
Investigations for hypercoagulable states Investigations for hypercoagulable states
Progression of ischemic stroke Progression of ischemic stroke
Strategies for acute stroke treatment Strategies for acute stroke treatment
The Plumbing Approach The Plumbing Approach
National Institute of Neurological Diseases and Stroke (NINDS) t-PA trial National Institute of Neurological Diseases and Stroke (NINDS) t-PA trial
NINDS t-PA Trial NINDS t-PA Trial
Symptomatic hemorrhages Symptomatic hemorrhages
NINDS t-PA Trial NINDS t-PA Trial
Neuroprotection Neuroprotection
Cerebral response to declining blood flow Cerebral response to declining blood flow
Stroke Syndrome: Slide 73 Stroke Syndrome: Slide 73
Neuroprotectant mechanisms and some tested compounds Neuroprotectant mechanisms and some tested compounds
Timing, timing, timing Timing, timing, timing
Immediate management of patients with suspected stroke Immediate management of patients with suspected stroke
Immediate management of patient with suspected stroke Immediate management of patient with suspected stroke
Short-term complications Short-term complications
Prevention of DVT Prevention of DVT
The Magic Hour The Magic Hour
Time: Traditional vs. Emerging Views Time: Traditional vs. Emerging Views
Brain Attack! Brain Attack!