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Author: Alvar W Gustafson, Ph.D.
G4-1:Lymph Node, Cortex
Stain:Hematoxylin & Eosin
Description:Section of lymph node through cortex showing an artificial separation of the tissue across this specimen from upper left to lower right. This artifact most likely is a tear that was caused in preparation when the section were spread out on the slide. However, when these separations are widespread throughout a specimen and extend in several directions, they can also be cracks in the tissue caused by too hard a specimen (usually overly dehydrated) striking the microtome knife during sectioning. (ag01)